Voltaren Science - Diclofenac

Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source

Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,4

Relative potency of diclofenac, ketoprofen and ibuprofen

Diclofenac is a potent anti-inflammatory agent1

Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2,4

Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.5

Diclofenac targets inflammation to strike pain at its source

Diclofenac-containing products

Voltaren Triple Effect 1.16% Emulgel

Voltaren Triple Effect 1.16% Emulgel

It is specifically formulated to treat common types of pain - including joint pain; sprains and strains; and back and neck pain

Diclofenac – a potent anti-inflammatory ingredient1

Diclofenac-containing products

Diclofenac-containing products

Learn more about Voltaren products that contain this potent anti-inflammatory ingredient.1

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Patient care

Patient care resources

Access educational resources to share with your patients, to help them have a better understanding of their pain condition.

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Educational resources

Educational resources

Access detailed clinical information about diclofenac.

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