Voltaren Science - Diclofenac
Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source
Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,4
Diclofenac is a potent anti-inflammatory agent1
Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2,4
Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.5
Diclofenac targets inflammation to strike pain at its source
Diclofenac-containing products
Voltaren Triple Effect 1.16% Emulgel
It is specifically formulated to treat common types of pain - including joint pain; sprains and strains; and back and neck pain