Stannous fluoride formulation

Clinically proven ingredient for tooth sensitivity relief

Sensodyne’s stannous fluoride formulation offer lasting protection from dentine hypersensitivity with twice-daily use.

Stannous fluoride occludes exposed dentine tubules

Insoluble stannous salts embedding into dentine

Stannous fluoride occludes exposed dentine tubules, helping prevent the movement of fluid^1,2–4

Representative FIB-SEM image of dentine tubules treated with Sensodyne stannous fluoride formulations, combining multiple imaging techniques (STEM-EDS, DSIMS, FIB-SEM/EDS). The insoluble stannous salts are shown to extend up into the dentine tubules.^3,4

DSIMS, dynamic secondary ion mass spectrometry; FIB-SEM/EDS, focused ion beam scanning electron microscope/energy-dispersive spectroscopy; STEM-EDS, scanning transmission electron microscope energy-dispersive spectroscopy

Clinical summary

Clinically proven relief

Stannous fluoride is delivered in a non-aqueous formulation that is primed to react in the mouth
The non-aqueous formulation ensures stannous fluoride becomes active when in contact with saliva
Dentine tubule occlusion that can withstand exposure to dietary acids⁵

In vitro SEM images of the dentine surface after 2 minutes’ exposure to Sensodyne toothpaste with stannous fluoride slurries twice daily.⁵

SEM, scanning electron microscope

Study summary
Reduction in dentine hypersensitivity from the first brush with Sensodyne Rapid Action⁶

Sensodyne Rapid Action with stannous fluoride is clinically proven to relieve sensitivity from the first brush.⁶

A study by Creeth J et al showed 7% reduction in Schiff score from baseline after first brush, and 18% reduction in Schiff score from baseline after first brush⁶

Find out more about Sensodyne Rapid Action

Chart adapted from Creeth J et al, 2019

Clinical summary
Sustained relief in dentine hypersensitivity with continued, twice daily⁷

A 63% reduction in dentine hypersensitivity has been shown after 8 weeks of brushing with stannous fluoride*.⁷

Chart adapted from Parkinson et al. 2015

^*Percentage improvement in Schiff score vs fluoride-only toothpaste after 8 weeks, test 0.454% w/w stannous fluoride toothpaste vs. control fluoride-only toothpaste

Clinical summary